Ingxoxo ngengozi yesoya kanye nomdlavuza ibilokhu iyingxabano, ikakhulukazi ngenxa yokukhathazeka ngokuqukethwe kwayo kwe-phytoestrogens. Ama-Phytoestrogens, ikakhulukazi ama-isoflavone atholakala ku-soya, ahlolisisiwe ngoba amakhemikhali afana ne-oestrogen, ihomoni eyaziwa ngokuba nomthelela ekuthuthukisweni komdlavuza othile. Ukuqagela kwasekuqaleni kwaphakamisa ukuthi lezi zinhlanganisela zingasebenza njenge-estrogen emzimbeni, okungase kwandise ingozi yomdlavuza. Lokhu kuye kwaholela ezihlokweni ezihlaba umxhwele nokukhathazeka okusabalele ngokuphepha kwesoya. Kodwa-ke, ucwaningo lwakamuva ludweba isithombe esihlukile, luveza ukuthi isoya ingase, empeleni, inikeze izinzuzo zokuzivikela kumdlavuza.

Ukuqonda Phytoestrogens

I-Phytoestrogens yizinhlanganisela ezithathwe ezitshalweni ezinesakhiwo esifana ne-estrogen, ihomoni eyinhloko yocansi yabesifazane. Naphezu kokufana kwawo kwesakhiwo, ama-phytoestrogens abonisa imiphumela ye-hormonal ebuthaka kakhulu uma kuqhathaniswa ne-endogenous estrogen. Izinhlobo eziyinhloko zama-phytoestrogens zihlanganisa ama-isoflavone, ama-lignans, nama-coumestan, kanti ama-isoflavone avame kakhulu emikhiqizweni yesoya.

Ama-Phytoestrogens alingisa i-estrogen ngenxa yesakhiwo sawo samakhemikhali, esiwavumela ukuba abophe ama-estrogen receptors emzimbeni. Kodwa-ke, ukuhlobana kwabo okubophayo kuphansi kakhulu kunokwe-estrogen yemvelo, okuholela kumphumela we-hormonal obuthaka kakhulu. Lokhu kufana ne-estrogen kuye kwaholela ekukhathazekeni ngomthelela wazo ezimeni ezizwela amahomoni, ikakhulukazi umdlavuza webele, othonywa amazinga e-estrogen.

Izinhlobo ze-Phytoestrogens

⚫️ Ama-Isoflavone: Atholakala kakhulu emikhiqizweni yesoya nesoya, ama-isoflavone afana ne-genistein ne-daidzein angama-phytoestrogens afundwa kakhulu. Baziwa ngamandla abo okusebenzelana nama-estrogen receptors futhi kuvame ukugxila ocwaningweni mayelana nemiphumela yabo yezempilo.

⚫️ Ama-Lignans: Akhona ngembewu (ikakhulukazi ama-flaxseeds), okusanhlamvu okuphelele, nemifino, ama-lignans aguqulwa amagciwane e-gut abe ama-enterolignans, nawo anomsebenzi we-estrogenic omncane.

⚫️ Ama-Coumestan: Lawa awavamile kodwa atholakala ekudleni okufana nama-alfalfa sprouts nama-split peas. Ama-Coumestan nawo anemiphumela efana ne-estrogen kodwa ayifundwa kakhulu.

Ukuqeda Izinganekwane: Imiphumela Yocwaningo

Umdlavuza Wendlala Yesinye

Enye yezindawo eziphoqelela kakhulu zocwaningo mayelana nemiphumela yezempilo ye-soya igxile kumdlavuza wendlala yesinye, uhlobo lomdlavuza odlangile emadodeni. Ucwaningo lokuhlola olwenziwa emazweni ase-Asia, lapho ukusetshenziswa kwesoya kuphezulu kakhulu, kuveza amazinga aphansi kakhulu omdlavuza wendlala yesinye uma kuqhathaniswa namazwe aseNtshonalanga. Lokhu kubuka okuthakazelisayo kwenze ososayensi ukuba bajule ebudlelwaneni obuphakathi kokudla isoya nobungozi bomdlavuza.

Ucwaningo olunzulu luveza ukuthi ukusetshenziswa kwesoya kuhlotshaniswa nokunciphisa ngamaphesenti angama-20-30 engcupheni yokuba nomdlavuza wendlala yesinye. Lo mphumela wokuvikela kucatshangwa ukuthi uvela kuma-isoflavone akhona ku-soya, angase aphazamise ukukhula kwamangqamuzana omdlavuza noma abe nomthelela emazingeni e-hormone ngendlela enciphisa ingozi yomdlavuza. Ngaphezu kwalokho, isoya ibonakala inemiphumela enenzuzo ngisho nangemva kokuqala komdlavuza wendlala yesinye. Ucwaningo lubonisa ukuthi isoya ingasiza ekubambezeleni ukuqhubeka kwesifo futhi ithuthukise imiphumela yesiguli, inikeze izinzuzo ezingaba khona kulabo asebevele batholakale benomdlavuza wendlala yesinye.

Umdlavuza Webele

Ubufakazi obuphathelene nomdlavuza webele kanye nokusetshenziswa kwesoya buyakhuthaza ngokufanayo. Ucwaningo oluningi luye lwabonisa ngokungaguquki ukuthi ukudla okuphezulu kwe-soya kuhlotshaniswa nokuncipha kwezigameko zomdlavuza webele kanye nesibeletho. Ngokwesibonelo, ucwaningo luye lwathola ukuthi abesifazane abadla inkomishi eyodwa yobisi lwesoya nsuku zonke noma njalo abadla ingxenye yenkomishi ye-tofu banengozi ephansi ngamaphesenti angu-30 yokuba nomdlavuza webele uma kuqhathaniswa nalabo abadla kancane isoya noma abangayidli nhlobo.

Izinzuzo zokuvikela zesoya kukholakala ukuthi zigqama kakhulu lapho yethulwa kusenesikhathi. Phakathi nenkathi yobusha, izicubu zamabele ziyakhula, futhi ukukhetha kokudla kungathonya lesi sikhathi esibucayi. Kodwa-ke, izinzuzo zokusebenzisa isoya azigcini kubantu abasebasha. Ucwaningo Lwezempilo Olunempilo Lwabesifazane lugqamisa ukuthi abesifazane abanomlando womdlavuza webele abahlanganisa imikhiqizo yesoya ekudleni kwabo banganciphisa kakhulu ingozi yokubuya futhi nokufa komdlavuza. Lokhu kusikisela ukuthi isoya inganikeza izinzuzo zokuvikela kuzo zonke izigaba zokuphila ezihlukene, okuhlanganisa ngemva kokuxilongwa komdlavuza.

Ucwaningo luchitha inganekwane yokuthi ukusetshenziswa kwesoya kwandisa ingozi yomdlavuza futhi esikhundleni salokho kusekela umbono wokuthi isoya ingadlala indima yokuvikela ngokumelene nomdlavuza wendlala yesinye kanye nomdlavuza wamabele. Imiphumela enenzuzo ebonwe ocwaningweni oluningi igcizelela ukubaluleka kokufaka isoya ekudleni okunomsoco, okuqinisa indima yayo njengokudla okukhuthaza impilo. Ubufakazi buphakamisa ukuthi ama-isoflavone e-soya nezinye izinhlanganisela zifaka isandla ekwehliseni ubungozi bomdlavuza kanye nemiphumela ethuthukisiwe yabantu abanomdlavuza, okwenza isoya ibe ingxenye ebalulekile yamasu okudla okuhloswe ngawo ukuvimbela nokuphatha umdlavuza.

Ukuvumelana Kwesayensi Nezincomo

Ushintsho ekuqondeni kwesayensi mayelana nengozi yesoya nesifo somdlavuza kubonakala ezincomweni zokudla okubuyekeziwe. ICancer Research UK manje ikhuthaza izinguquko ezimbili ezibalulekile zokudla ukusiza ukunciphisa ingozi yomdlavuza webele: ukufaka amafutha ezilwane esikhundleni samafutha emifino kanye nokwandisa ukuthathwa kwe-isoflavones emithonjeni efana nesoya, uphizi nobhontshisi. Lesi siqondiso sisekelwe ebufakazini obukhulayo obuphakamisa ukuthi ukudla okusekelwe ezitshalweni okucebile kulezi zinhlanganisela kungaba nomthelela ekunciphiseni ingozi yomdlavuza kanye nemiphumela yezempilo engcono.